HIV vaccine: Large-scale clinical trial to start in South Africa to test vaccine regimen

A large clinical trial to test the safety and efficacy of an HIV vaccine is about to begin in South Africa. The study, known as HVTN 702, will last until 2020 and will assess whether the vaccine regimen can protect a group of healthy adults at risk of getting infected.The experimental vaccine regimen that will be tested is based on one that showed promising results in a landmark 2009 study – the Military HIV Research Program-led RV144 clinical trial in Thailand. The only difference is that the regimen has been slightly modified to match the HIV sub-type that is prevalent in South Africa.

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